Gary Cooper
Wild Bill Hickok
Jean Arthur
Calamity Jane
James Ellison
William "Buffalo Bill" Cody
Charles Bickford
John Lattimer
Helen Burgess
Louisa Cody
Porter Hall
Jack McCall
Paul Harvey
Yellow Hand
Victor Varconi
Painted Horse
John Miljan
General George A. Custer
Frank McGlynn Sr.
Abraham Lincoln
Granville Bates
Van Ellyn
Anthony Quinn
Cheyenne Indian
George 'Gabby' Hayes
Breezy
Mark Strong
Wells Fargo Agent (uncredited)
Frank Albertson
A Young Trooper
Purnell Pratt
Capt. Wood
Fred Kohler
Jake - A Teamster
Pat Moriarity
Sgt. McGinnis
Charles Judels
Tony - The Barber
Harry Woods
Quartermaster Sergeant
Francis McDonald
A River Gambler
George Ernest
A Boy
George MacQuarrie
Gen. Merritt
Fuzzy Knight
Dave
Everett Brown
Curtis Nero
Roustabout
Crew
Cecil B. DeMille
Director
Johnny Eckert
Stunts
Spike Spackman
Stunts
Jimmy Phillips
Stunts
Greg Whitespear
Stunts
Frank Cordell
Stunts
Bryan 'Slim' Hightower
Stunts
Ken Cooper
Stunts
Waldemar Young
Screenplay
Anne Bauchens
Editor
Dwight Franklin
Costume Design
Natalie Visart
Costume Design
Harold Lamb
Screenplay
Lynn Riggs
Screenplay
Roland Anderson
Art Direction
Hans Dreier
Art Direction
Joe De Young
Costume Design
George Antheil
Music
Victor Milner
Director of Photography
Harry Lindgren
Sound Recordist
Cecil B. DeMille
Producer
Barney Wolff
Special Effects
William H. Pine
Producer
Arthur Rosson
Second Unit Director
Louis Mesenkop
Sound Recordist
Richard Harlan
Assistant Director
William LeBaron
Executive Producer
George Robinson
Director of Photography