Season 21

Jimmy welcomes guests Johnny Knoxville and Olivia Cooke. Musical performance by BLACKPINK.

Jimmy welcomes guests Kathy Griffin, and Chad Kroeger and JT Parr. Musical performance by Madison Cunningham.

Jimmy welcomes guests John Boyega and Tyler James Williams. Musical performance by Weezer

Jimmy welcomes guests Allison Janney, Chris Estrada, and Frankie Quiñones. Musical performance by Yung Gravy.

Jimmy welcomes comic Amy Schumer, TV host Charlamagne Tha God, and a musical performance by Run the Jewels.

Jimmy welcomes TV host David Letterman and actor Tracy Morgan.

Jimmy welcomes actress Mila Kunis, actor Ramy Youssef, and a musical performance by Future.

Jimmy welcomes producer Ben Stiller, TV personality Desus Nice, and a musical performance by Yeah Yeah Yeahs.

Jimmy welcomes actor Jason Bateman and a musical performance by Action Bronson.

Charlie Hunnam ("Shantaram"), Iliza Shlesinger ("All Things Aside"), Musical Guests NAV feat. Don Toliver

Jimmy welcomes actor Norman Reedus, actress Danielle Deadwyler, and a musical performance by Miranda Lambert.

Keanu Reeves ("BRZRKR: Vol. 2"), Judd Apatow ("Bros"), Musical Guests Phoenix

Actor David Spade (podcast series, "Fly on the Wall with Dana Carvey and David Spade"); professional baseball player Mookie Betts (documentary "Jackie Robinson: Get to the Bag", Los Angeles Dodgers); Flo performs.

Former professional basketball player Magic Johnson; comic Fortune Feimster; Wet Leg performs.

Actress Jamie Lee Curtis; actor Lucas Bravo; Midland and Jon Pardi perform.

Actress Jessica Chastain; Maren Morris talks and performs.

Actors George Clooney and Julia Roberts ("Ticket to Paradise"); Omar Apollo performs.

Actor Josh Gad; actress Pamela Adlon; comic Ariel Elias.

Actress Charlize Theron; race car driver Lewis Hamilton; Armani White performs.

Actresses Lupita Nyong'o, Danai Gurira and Letitia Wright ("Black Panther: Wakanda Forever"); Duran Duran performs.

Filmmaker Quentin Tarantino; actor Tenoch Huerta; Edgar Winter sits in with Cleto and the Cletones.

Actress Gwyneth Paltrow; comic Patton Oswalt.

Actress Mindy Kaling; actor Frank Grillo; Goose performs.

Nick Kroll, Yvonne Strahovski, Viagra Boys

Rob McElhenney, Emayatzy Corinealdi

Dana Carvey, Jonathan Majors, SoFaygo

Bill Maher, George Conway, Breland

Jason Momoa, Luke Grimes, Lainey Wilson

Brian Tyree Henry, Lizzy Caplan

Chris Hemsworth, Meghann Fahy, Maneskin

Amy Adams, Maya Rudolph, Jenna Ortega, Bush

Kumail Nanjiani, Pink

Patrick Dempsey, Nicholas Hoult, the Backseat Lovers, Billy Gibbons

Carey Mulligan, Josh Groban, Angela Alvarez

Kristen Bell, David Shrigley, Noah Kahan

Kathryn Hahn, Dominic West, Beach Weather

Billy Crystal, Kate Berlant, Camilo

David Harbour, Lisa Ann Walter, Thee Sacred Souls

Don Cheadle, Zoey Deutch, Chris Isaak

George Lopez, Haley Lu Richardson, Madi Diaz

Janelle Monáe, Sadie Sink, Rita Wilson, Smokey Robinson

Will Ferrell, Colson "Machine Gun Kelly" Baker, the Linda Lindas

Jean Smart, Wes Bentley, Charley Crockett

Michelle Obama, Marc Maron

Sigourney Weaver, Jovan Adepo, Dawes

Margot Robbie, Jeremy Allen White, the White Buffalo

Brendan Fraser, Diego Calva, Weezer

Seth Rogen, Diego Calva, Aoife O'Donovan featuring Allison Russell

Anna Kendrick, Jermaine Fowler, Sabrina Carpenter

Laura Dern, Jeremy Allen White, Matt Maeson

Joel McHale, Ali Wentworth, Molly Tuttle

Austin Butler, Bella Ramsey, Iggy Pop, Peyton Manning, Eli Manning

Octavia Spencer, Ramon Rodríguez, Renee Rapp

Bryan Cranston

Viola Davis, Judd Hirsch, Chase Rice

Danny DeVito, Lucy DeVito, Travis Bennett, A Boogie wit da Hoodie

Rob Lowe, Storm Reid, Seal

Jennifer Lopez, Chris Perfetti, Fall Out Boy

Lily Tomlin, Jane Fonda, Rita Moreno, Sally Field, Jacob Latimore

David Duchovny, Zach Shallcross, Lukas Graham, Mickey Guyton

Julia Louis-Dreyfus, Rose Byrne, Bobby Cannavale

D'Arcy Carden, Hailey Whitters

George Clooney, Snoop Dogg, Coldplay

Salma Hayek Pinault, Billy Crudup, Justine Skye

Pamela Anderson, Mike Lindell, Fall Out Boy

Nick Offerman, Kerry Condon, Sofia Carson, Diane Warren

Reese Witherspoon, Wesley Kimmel, "Science Bob" Pflugfelder

Cate Blanchett, Patrick Mahomes, Dave Franco

Milo Ventimiglia, Charles Barkley, Paramore

Orlando Bloom, Lauren Ash, Jordan Davis

Katy Perry, Lionel Richie, Mike Epps, Beck

Wanda Sykes, RZA, Bailey Zimmerman

Keri Russell, Ms. Pat, Logic

Anthony Mackie, Chris Distefano, Gracie Abrams

Tom Cruise, Camila Morrone

Michael B. Jordan, Blake Shelton

Courteney Cox, Ike Barinholtz

Jon Favreau, Nicole Byer, Tove Lo

Paul Mescal, Kali Uchis

Owen Wilson, Guillermo del Toro

Seth Rogen, Rachel Zegler

David Letterman, Dominique Fishback

Andy Samberg, Lukas Gage, RAYE

Jennifer Hudson, Donnie Yen, Larkin Poe

Julie Bowen, Jamie Demetriou, Depeche Mode

Molly Shannon, Giancarlo Esposito, Nickel Creek

Jeff Goldblum, Teyana Taylor, Jeff Goldblum & the Mildred Snitzer Orchestra

Chris Pine, Dave Burd, The War and Treaty

Ben Affleck, Nicholas Braun, Chlöe

Jason Bateman, Ali Wong, Stray Kids

Viola Davis, Julius Tennon, Brett Goldstein, Daniel Caesar

Jeremy Renner, Metallica

Carol Burnett, Wendi McLendon-Covey, Metallica

Quinta Brunson, Metallica

Bill Hader, Jane Goodall, Metallica

Freddie Highmore, Amanda Peet, Dinner Party

Luke Bryan, Jeff Hiller, GloRilla

Patrick Stewart, Bridget Everett, Gorillaz featuring Beck

Jake Gyllenhaal, Whitney Cummings, boygenius

James Corden, Richard Madden, They Might Be Giants

John Mulaney, India Amarteifio, Cannons

Pierce Brosnan, Abby Ryder Fortson, New West

Chris Pratt, Lukas & Micah Nelson

1. Charlie Day ("Fool's Paradise") 2. Padma Lakshmi ("Taste the Nation with Padma Lakshmi") 3. Musical Guest Bebe Rexha